Alexandre Meloux

  • +33 3 80 39 34 93
  • 375
    UFR Sciences de Santé
    7 boulevard Jeanne d’Arc
    21079 DIJON Cedex


Neurology, Cardiology, Stroke, Physical activity, Neuroplasticity, BDNF, GDF-15

2016-2019 Physiology PhD at Burgundy University, Dijon in « accueil » team « Cerebro-Cardiovascular Pathophysiology and Epidemiology » directed by Pr C. VERGELY, entitled « Cerebral ischemia impacts on heart function and sensitivity to ischemia »
2015-2016 Research Master’s degree CardioMetabolic and Nutritional Regulations at Claude Bernard University, Lyon. Internship within UMR 866 « Lipids, Nutrition, Cancer » entitled « Cerebral ischemia induces myocardial oxidative stress and contractile dysfunction in rat »
2014-2015 1st year of pharmacy internship, sector Pharmaceutical Innovation and Research, Reims: Semester 1 = Invitation to tender, matériovigilance and traceability; Semester 2 = Clinical trials, temporary authorization to use and retrocession
2008-2014 Pharmacy curriculum

Physical activity and cognition: BDNF and signaling pathways

Neuroplasticity: Impact of endothelial BDNF deletion

Human physiology, Pharmacology, Pathophysiology, Communication


Scientific articles in international or national peer-reviewed journals

Cottin Y, Issa R, Benalia M, Mouhat B, Meloux A, Tribouillard L, Bichat F, Rochette L, Vergely C, Zeller M (2020) Association between Serum Osteoprotegerin Levels and Severity of Coronary Artery Disease in Patients with Acute Myocardial Infarction. Journal of Clinical Medicine 10(19):4326 (IF : 4,24)
Hannappe MA, Arnould L, Meloux A, Mouhat B, Bichat F, Zeller M, Cottin Y, Binquet C, Vergely C, Creuzot-Garcher C, Guenancia C (2020) Vascular density with optical coherence tomography angiography and systemic biomarkers in low and high cardiovascular risk patients. Scientific Reports 10(1):16718 (IF : 4,38)
Meloux A, Bejot Y, Rochette L, Cottin Y, Vergely C (2020) Brain-Heart Interactions During Ischemic Processes Clinical and Experimental Evidences. Stroke 51(2):679-686 (IF : 7,91)
Meloux A, Rochette L, Maza M, Bichat F, Tribouillard L, Cottin Y, Zeller M, Vergely C (2020) Growth Differentiation Factor-8 (GDF8)/Myostatin Is a Predictor of Troponin I Peak and a Marker of Clinical Severity after Acute Myocardial Infarction. Journal of Clinical Medicine 9(1):116. (IF : 4,24)
Rochette L, Mazini L, Meloux A, Zeller M, Cottin Y, Vergely C, Malka G (2020) Anti-Aging Effects of GDF11 on Skin. International Journal of Molecular Sciences 21(7):2598 (IF : 5,92)
Rochette L, Meloux A, Zeller M, Malka G, Cottin Y, Vergely C (2020) Mitochondrial SLC25 Carriers: Novel Targets for Cancer Therapy. Molecules. Molecules 225(10):2417 (IF : 4,41)
Rochette L, Meloux A, Zeller M, Cottin Y, Vergely C (2020) Functional roles of GDF15 in modulating microenvironment to promote carcinogenesis. Biochimica Et Biophysica Acta-Molecular Basis of Disease 1866(8):165798 (IF : 5,19)
Breniere C, Meloux A, Pedard M, Marie C Thouant P, Vergely C, et al. (2019) Growth Differentiation Factor-15 (GDF-15) Is Associated With Mortality in Ischemic Stroke Patients Treated With Acute Revascularization Therapy. Frontiers in Neurology 10:611. (IF : 2,635)
Rochette L, Meloux A, Rigal E, Zeller M, Cottin Y, Vergely C (2019) The Role of Osteoprotegerin and Its Ligands in Vascular Function. International Journal of Molecular Sciences 20(3):705 (IF : 4,56)
Meloux A, Rigal E, Rochette L, Cottin Y, Bejot Y, Vergely C (2018) Ischemic Stroke Increases Heart Vulnerability to Ischemia-Reperfusion and Alters Myocardial Cardioprotective Pathways. Stroke 49(11):2752-2760 (IF : 6.06)
Rochette L, Meloux A, Rigal E, Zeller M, Cottin Y, Vergely C (2018) The role of osteoprotegerin in the crosstalk between vessels and bone: Its potential utility as a marker of cardiometabolic diseases. Pharmacology & Therapeutics 182:115-132. (IF : 9,40)
Rochette L, Meloux A, Rigal E, Zeller M, Cottin Y, Malka G, Vergely C (2018) Regenerative Capacity of Endogenous Factor: Growth Differentiation Factor 11; a New Approach of the Management of Age-Related Cardiovascular Events. International Journal of Molecular Sciences 19(12):3998. (IF: 4,18)