Anne Tessier

  • Professor of Physiology
  • +33 3 80 39 34 92
  • Room N° 371
    UFR Sciences de Santé
    7 boulevard Jeanne d’Arc
    21079 DIJON Cedex


  • Molecular Neurobiology
  • BDNF-dependent neuroplasticity
  • Exercise and electromyostimulation : effect on neuroplasticity


2007 Accreditation to supervise research, University of Burgundy, INSERM U1093
1993-96 Doctoral thesis, University of « Claude Bernard, Lyon I, INSA de Lyon » in the laboratory of Biochemistry and Pharmacology INSERM U352
1992-93 Research Master’s degree level 2 in Biochemistry, University of « Claude Bernard, Lyon I, INSA de Lyon »
1987-96 Pharmacist, University of « Claude Bernard, Lyon I »
  • Interactions between lipid mediators and prolactin in the differentiation of rat stromal uterine cells
  • Study of physical activity on neuroplasticity after brain injury
  • Relationship between cardiovascular health and cognition: role of endothelial BDNF
  • Muscle-brain crosstalk

Cell biology, human physiology, pharmacology, pathophysiology and treatment of diseases of the central nervous system


Scientific articles in international or national peer-reviewed journals

Pedard M, Quirié A, Tessier A, Garnier P, Totoson P, Demougeot C, Marie C (2021) A reconciling hypothesis centred on brain-derived neurotrophic factor to explain neuropsychiatric manifestations in rheumatoid arthritis. Rheumatology 60(4):1608- (IF : 7,09)
Totoson P, Peyronnel C, Quirié A, Pédard M, Cefis M, Bermont L, Prigent-Tessier A, Prati C, Tournier M et al (2021) Tofacitinib improved peripheral endothelial dysfunction and brain-derived neurotrophic factor levels in the rat adjuvant-induced arthritis model. Fundamental & Clinical Pharmacology 36(2):363-374. (IF : 2,85)
Totoson P, Santini C, Tessier A, Marie C, Demougeot C (2021) Endothelial TrkB receptor activation controls vascular tone of rat middle cerebral artery. Vascular Pharmacology (IF : 3,86)
Cefis M, Quirié A, Pernet N, Marie C, Garnier P, Prigent-Tessier A (2020) Brain-Derived Neurotrophic Factor Is a Full Endothelium-Derived Factor in Rats. Vascular Pharmacology 128‑129:106674. (IF : 5.77)
Pedard M, Quirié A, Tessier A, Garnier P, Totoson P, Demougeot C, Marie C (2020) A Reconciling Hypothesis Centered on Brain-Derived Neurotrophic Factor to Explain Neuropsychiatric Manifestations in Rheumatoid Arthritis. Rheumatology 60(4):1608-1619. (IF : 7.58)
Cefis M, Prigent-Tessier A, Quirié A, Pernet N, Marie C, Garnier P (2019) The effect of exercise on memory and BDNF signaling is dependent on intensity. Brain Structure and Function 224(6):1975-1985 (IF : 3,3)
Pedard M, Cefis M, Ennequin G, Quirie A, Garnier P, Prigent-Tessier A, et al. (2019) Brain-derived Neurotrophic Factor Pathway after Downhill and Uphill Training in Rats. Medicine and Scienc in Sports and Exercise. 51:27–34. (IF : 4)
Marie C, Pedard M, Quirié A, Tessier A, Garnier P, Totoson P, Demougeot C (2018) Brain-derived neurotrophic factor secreted by the cerebral endothelium: A new actor of brain function? Journal of Cerebral Blood Flow and Metabolism 38(6):935-949. (IF : 6,04)
Pedard M, Quirie A, Totoson P, Verhoeven F, Garnier P, Tessier A, Demougeot C, Marie C (2018) Corrigendum to “Vascular brain-derived neurotrophic factor pathway in rats with adjuvant-induced arthritis: Effect of anti-rheumatic drugs”.Atherosclerosis 274:77-85 (IF : 4,26)
Pedard M, Quirié A, Garnier P, Tessier A, Demougeot C, Marie C (2018) The cerebral brain-derived neurotrophic factor pathway, either neuronal or endothelial, is impaired in rats with adjuvant-induced arthritis. Connection with endothelial dysfunction. Frontiers in Physiology 8:1125. (IF : 3.2)
Monnier A, Prigent-Tessier A, Quirie A, et al (2017) Brain-derived neurotrophic factor of the cerebral microvasculature: a forgotten and nitric oxide-dependent contributor of brain-derived neurotrophic factor in the brain. Acta Physiologica 219:790–802. (IF : 5.93)
Moretto J, Guglielmetti A-S, Tournier-Nappey M, Martin H, Prigent-Tessier A, Marie C and Demougeot C (2017) Effects of a chronic l-arginine supplementation on the arginase pathway in aged rats. Experimental Gerontology 90:52–60. (IF : 3.22)
Verhoeven F, Totoson P, Maguin-Gate K, Prigent-Tessier A, Marie C, Wendling D, Moretto J, Prati C, Demougeot C (2017) Glucocorticoids improve endothelial function in rheumatoid arthritis: a study in rats with adjuvant-induced arthritis. Clinical and Experimental Immunology 188:208–18. (IF : 3.54)
Verhoeven F, Totoson P, Marie C, Prigent-Tessier A, Wendling D, Tournier-Nappey M, Prati C, Demougeot C (2017) Diclofenac but not celecoxib improves endothelial function in rheumatoid arthritis: A study in adjuvant-induced arthritis. Atherosclerosis 266:136–44. (IF : 4.47)
Banoujaafar H, Monnier A, Pernet N, Quirie A, Garnier P, Prigent-Tessier A, Marie C (2016) Brain BDNF levels are dependent on cerebrovascular endothelium-derived nitric oxide. European Journal of Neuroscience 44:2226-2235 (IF : 2.94)
Totoson P, Maguin-Gate K, Prigent-Tessier A, Monnier A, Verhoeven F, Marie C, Wendling D, Demougeot C (2016) Etanercept improves endothelial function via pleiotropic effects in rat adjuvant-induced arthritis. Rheumatology (Oxford) 55:1308-1317. (IF : 4.82)